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Horses and ponies that are nervous, tense, show an inability to learn and concentrate, have tight, tense muscles, are slow to warm up and have sore or tight backs can show improvement when given Quiessence®. Giving additional Magnesium and Chromium to cresty-necked, insulin resistant, founder prone horses and ponies may help reduce the tendency to develop endocrine-related laminitis.
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Quiessence® is a pelleted, palatable Magnesium and Chromium formula designed to support calm, balanced behavior in equines. It may help animals that are cresty-necked to reduce the crest, and may also help reduce the tendency to founder by supporting normal glucose metabolism and increasing peripheral circulation. Quiessence® is legal for competition with no known side effects.
Magnesium works closely with Potassium and Calcium in cells, and a deficiency of Magnesium often results in low interstitial Potassium and the corresponding symptoms. Muscles are the main body store for Magnesium and, if there is a deficiency in the diet, the body draws Magnesium from the muscles. If enough is withdrawn, muscle Magnesuim levels drop, resulting in neuromuscular problems. Therefore, horses and ponies that are nervous, tense, show an inability to learn and concentrate, have tight, tense muscles, are slow to warm up and have sore or tight backs can show improvement when given Quiessence®.
Giving additional Magnesium and Chromium to cresty-necked, insulin resistant, founder prone horses and ponies may help reduce the tendency to founder. Magnesium supports peripheral circulation to the extremities, which may ease sore feet and promote healing in foundered animals. Chromium has been shown to improve glucose clearance by improving insulin sensitivity in various classes of livestock. Quiessence® provides high levels of Magnesium and Chromium in a pelleted form.
In a study we conducted in 2002-2003, founder prone horses with thick, cresty necks showed a reduction in neck thickness and hardness when fed a Magnesium supplement. The reduction in neck thickness made the horses easier to manage, ride and handle, as well being more aesthetically pleasing.
Magnesium deficiency usually shows as nervousness, muscular tension, inability to relax, irritability, hyper-sensitivity to touch or sounds, and poor memory retention.
Some causes of Magnesium deficiencies:
Active Ingredients Per 1oz:
Inactive Ingredients: Lignin Sulfonate, Banana Flavor, Distillers Grains, Powersweet, Sodium Chloride, Vegetable Oil, Wheat Mids.
Quiessence® provides 4.2 grams of elemental Magnesium (4g from Magnesium Oxide and 0.1 g (100 mg) from more bioavailable Magnesium Proteinate) per 1oz serving.
Take a look at this testimonial that sums it up and reflects what I hear from many horseowners:
"Taweela is not just a horse, she is my buddy and lifelong friend. I bought her when she was 18 months, and she is now 13 years young, which is the prime of life for an Arabian. Taweela is a high-level endurance performer who lives to see what is around the next corner. For endurance enthusiasts, this is the horse to have. However, with all of her wonderful traits, Taweela has a few challenge areas. The first is that after a Winter break, when Spring comes around and she is out on pasture for a short time, she starts getting obese. Her neck gets extremely cresty, and if not acted on quickly, she could founder.
The second challenge is that she is extremely high-strung and nervous. She actually paces in the trailer and while we are 'standing' in place. She can be quite a handful, and doesn't seem to calm down even after a long ride.
The third challenge is that the muscles on the entire length of her back have a hard time relaxing after a ride. I originally attributed this to saddle fit, and have spent thousands of dollars on a special saddle and all sorts of special pads. I have just accepted these things about her and dealt with them over the years because she is worth the extra effort, and I love her. Enter Quissence.
I saw Dr. Getty's ad for Quiessence on her Web site, and decided to try it. I used the maximum dose on her until the crest in her neck started going down and getting softer. She also started getting calmer. She seemed to be a lot more relaxed. This took about 2 weeks. I then switched to the normal dose. The change has been amazing. Taweela is still the go-go girl I know and love, but she is so much more calm. She doesn't go crazy on the road home, and recently, after a short ride, she walked almost all the way home with a loose rein. I also checked her back after the ride, and there was no stiffness.
I did not know that an imbalance in Magnesium could cause so many problems, not only physical but mental as well. Quiessence pellets are palatable and she eats every one. Taweela and I now have a much better relationship because she is able to focus more and relax. Thanks Dr. Getty!"
~ Barbara P., Oregon
*Quiessence is shipped via UPS (via USPS for 5 lb bags) within two days. Free shipping is offered anywhere within the continental U.S. Shipping to Hawaii and Alaska will incur additional shipping charges. Please email GettyEquineNutrition@gmail.com or call 940-272-0001 before ordering for a shipping quote to these areas.
Canadian Orders: For orders in Canada, please contact Dr. Getty for assistance in finding dealers in Canada.
By Dr. Melyni Worth, Foxden Equine
Magnesium absorption in equines has not been fully investigated and most of the information that we have is extrapolated from ruminant studies, rat studies and human studies. There is considerable difference in Magnesium absorption in each of these species, and thus we do not, at this time, fully understand the exact sites and mechanisms of Mg absorption in the horse.
In humans there appears to be 3 different pathways of absorption, there is passive diffusion, an active diffusion and solvent drag. The bulk of Mg absorption (in humans) occurs in the small intestine, with a secondary site in the descending colon. In horses diffusion uptake is believed, to be primarily in the colons, however there is also some uptake in the distal small intestine. The solvent drag uptake is believed to be primarily in the small intestine.
The mechanisms of diffusion both passive and active require the presence of Mg and Ca ions in the gut lumen to be in a ratio to one another, as one of the transport mechanisms (the active) is not specific to either Mg or Ca, but picks up bivalent cations indiscriminately.
The ‘solvent drag’ mechanism includes the use of the mineral ion bound to proteins, as the proteins are picked up actively they ‘carry’ the mineral ion along with them. This mechanism is particularly effective if the Mg ion is bound to an essential amino-acid, as the essential aa’s are most actively absorbed. Thus Mg bound to methionine, or aspartate is absorbed faster and more efficiently, since those aa’s are more efficiently absorbed. This pathway acts along side the two diffusion pathways and produces a considerable increase in the amount of Mg absorbed from the gut.
Thus to supply the Mg most efficiently, it is best to supply the Mg as both a salt and as a proteinate, this means that the Mg can be absorbed by all 3 pathways. Thus increasing the amount that is absorbed in a given time and for a given dose.
Miner Electrolyte Metab. 1990;16(2-3):174-80.
Despite considerable research on magnesium (Mg) absorption there is still uncertainty regarding the site and mechanism of intestinal Mg transport. A careful review of the literature indicates that while Mg is absorbed throughout the intestine, the predominate site is the distal small intestine. There are three mechanisms by which Mg has been shown to cross the intestine:passive diffusion, solvent drag, and active transport. The importance of each of these mechanisms to total Mg absorption is discussed. Studies in both humans and experimental animals indicate that passive diffusion through the paracellular pathway accounts for the majority of Mg absorbed. Investigators have also consistently demonstrated the existence of a saturable component. Studies in everted gut sacs, however, have failed to demonstrate that Mg is actively transported against a concentration gradient in young or adolescent rats. Recent studies using the Using chamber have documented that Mg is actively transported in the descending colon.
Magnes Res. 1991 Mar;4(1):9-22.
Mg transport across various segments of the rat small and large bowel was measured in the absence of electrochemical gradients and using the voltage clamp technique. In the mucosa-to-serosa (ms) Mg flux across the duodenum, ileum, and colon a cellular part is involved, amounting to 40-70% of the total ms Mg flux measured across the short-circuited tissue. However, serosa-to-mucosa (sm) Mg flux is purely passive, suggesting that net Mg transport is largely determined by convectively driven Mg flux across the paracellular pathway. Mg is absorbed across the colon and ileum but in the duodenum paracellularly it is secreted due to an 'anomalous solvent drag effect'. Mg in the caecum decreases cellular ms Ca transport but in the other segments only passive ms Ca flux is reduced by a decrease of the paracellular permeability for Ca, or by a Mg-induced decrease in water absorption. Mg transport across all segments is insensitive to 1,25(OH)2D3. Dexamethasone abolishes cellular Ca transport but stimulates paracellular ms Mg flux in the duodenum. It is concluded that in the rat (a) Mg and Ca are transported by distinct cellular and paracellular mechanisms; (b) Mg transport is largely confined to the paracellular pathway; (c) the ileum and the colon are the major sites for the gut regulation of Mg homeostasis.
Getty Equine Nutrition, LLC
Juliet M. Getty, Ph.D.
12608 Lignite Drive
Denton, TX 76207
Phone: (940) 272-0001
Juliet M. Getty, Ph.D. is an independent equine nutritionist offering nutrition services for all life stages and integrative support for disorders and diseases. Your horse's quality of life is Dr. Getty's priority.
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