Turmeric is a Winning Supplement for Insulin Resistance
By Juliet M. Getty, Ph.D.
Turmeric, an Asian spice, has an impressive resume of reducing inflammation, relieving pain, protecting against brain degenerative diseases, and suppressing insulin resistance. Research[i] has revealed that feeding turmeric to laboratory animals suffering from Type II diabetes (which involves insulin resistance) resulted in weight reduction and increased glucose utilization.[ii]
Turmeric also has potent antioxidant properties, making it valuable in reducing the inflammatory response caused by excess body fat. Reduction of oxidative stress due to inflammation can allow the horse to become more sensitive to leptin, as well as slow down the progression of equine Cushing's disease.
The active ingredient in turmeric is curcumin. It is fat soluble, so there must be some source of fat in the meal to promote its absorption (e.g., ground flax, chia seeds, rice bran, oils, etc.). Curcumin amounts to less than 5% of turmeric, therefore, the exact dosage is not clear; however, feeding 2 to 4 tablespoons of turmeric per day to the average-sized horse is very well tolerated.
[i] Kim, T., Davis, J., Zhang, A.J., et. al., 2009. Curcumin activates AMPK and suppresses gluconeogenic gene expression in hepatoma cells. Biochem Biophys Res Commun. 388(2), 377-382.
[ii] Zhang, D.W., Fu, M., Gao, S.H., and Liu, J.L., 2013. Curcumin and diabetes: A Systematic Review. Evidence-Based Complementary and Alternative Medicine, 2013.
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